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Mercedes ML W164 280CDI 4Matic OM642.940 190HP Engine ECU A6421506300 Automatic
SKU: A6421506300
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Used
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Mercedes ML W164 280CDI 4Matic OM642.940 190HP Engine ECU is a factory electronic engine control unit designed for versions with 4Matic all-wheel drive and an automatic transmission. As a component from the Electronic control modules and controllers group, it is responsible for the precise management of the diesel engine, ensuring stable parameters and proper communication with other vehicle systems. This used ECU is a sensible service solution, allowing for the restoration of drivetrain efficiency while maintaining compliance with Mercedes' factory electrical architecture.
Specifications and technical data
- SKU: A6421506300
- Mark: Mercedes (Genuine OE)
- Condition: Used
- OEM Part Number: A6421506300
- Substitutable numbers: A6421506300, A 642 150 63 00, 0281015634, 0 281 015 634
- Fuel type: Diesel
- Gearbox type: Automatic
- Category: ECUs & Computer Modules
Purpose and function of the engine control unit
The presented ECU is dedicated to the 190 HP OM642.940 diesel engine in the Mercedes ML W164 model with 4Matic drive and an automatic transmission. The module monitors key engine performance parameters, such as fuel dosage, boost pressure, injection corrections, and interaction with the all-wheel-drive system, which translates into smooth power delivery and proper response to load.
Thanks to its factory design, the ECU maintains full compatibility with the vehicle's communication bus, safety systems, and automatic transmission electronics. This is particularly important in 4Matic vehicles, where the engine controller works with multiple modules responsible for traction and driving stability.
Benefits of using an original ECU module
Using an original controller from the Electronic control modules and controllers group ensures:
- preservation of factory engine maps and drivetrain control logic,
- proper cooperation with the automatic transmission regarding gear shifting and torque management,
- consistency with OBD diagnostic systems and factory service procedures,
- the possibility of adaptation and coding according to the requirements of the specific vehicle configuration.
A used ECU module is a practical solution in the event of an original controller failure – it allows for reduced repair costs while maintaining the original Mercedes electronic architecture without the need for unreliable aftermarket replacements.
Integration with the diesel drivetrain and automatic transmission
The controller has been designed to work with a Diesel engine, which means it is matched to the specifics of high-pressure injection, turbocharger operation, and emission control systems. At the same time, the module is adapted for configuration with an automatic transmission, allowing it to correctly manage torque, driving modes, and gear shift responses.
Such a combination is particularly important in ML W164 class SUVs, where the controller must account for both comfortable and heavy-duty driving – from daily use to towing or off-road driving. A properly selected ECU minimizes the risk of communication errors between modules and facilitates subsequent diagnostics.
Practical application and selection by part numbers
When replacing an engine controller in a Mercedes ML W164, it is crucial to match the module by OEM number and interchangeable numbers, as well as to verify hardware and software compatibility with the specific vehicle version. This unit, as a used controller, may require procedures such as adaptation, coding, or potential immobilizer matching, performed by a specialized service center.
To better understand the principles of selecting and installing such components, it is worth checking the Global Parts guide: Used automotive electronics on board – why is it worth choosing second-hand ECU modules and sensors?. The article discusses selection by VIN/OEM, HW/SW compatibility issues, and practical aspects of installing used modules.
Expansion of the control system in a Mercedes
If you are planning a comprehensive repair or upgrade of the engine area in your Mercedes and need other elements from the same group, such as engine controllers, comfort modules, or other electronic management units, check the available parts in the Mercedes electronic control modules and controllers category.
This allows you to build a coherent set of electronic modules based on original components, which facilitates diagnostics, service, and the maintenance of stable operating parameters for the entire drivetrain.
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Ship to: United Kingdom
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Estimated delivery dates include sellers dispatch time, origin postcode,destination postcode and time of acceptance, and will depend on the postage service selected and receipt of cleared payment. Delivery times may vary, especially during peak periods.
Will usually dispatch within same working day if paid before 14:00 BST (excludes weekends and holidays). Expected dispatch time may vary and is based on sellers order cut-off time.
In the automotive store Global Parts, we offer fast and secure deliveries for our customers in United Kingdom, ensuring maximum compliance with local service standards. Each order is processed with the utmost attention, guaranteeing a fluid shopping process and a timely delivery. If you need assistance in choosing the right part, our team of consultants will be happy to help you find the right part for your vehicle and provide information on installation, availability and parameters of the selected components.










